That would vary depending on the immune system and the mucin production within the cell adenosquamous cells are more aggressive than squamous cells. This process is rare occurring in about 2.5 %
Stage I
Stage I is carcinoma strictly confined to the cervix; extension to the uterine corpus should be disregarded.
Stage IA: Invasive cancer identified only microscopically. All gross lesions even with superficial invasion are stage Ib cancers. Invasion is limited to measured stromal invasion with a maximum depth of 5 mm* and no wider than 7 mm. [Note: *The depth of invasion should not be more than 5 mm taken from the base of the epithelium, either surface or glandular, from which it originates. Vascular space involvement, either venous or lymphatic, should not alter the staging.]
Stage IA1: Measured invasion of the stroma no greater than 3 mm in depth and no wider than 7 mm diameter.
Stage IA2: Measured invasion of stroma greater than 3 mm but no greater than 5 mm in depth and no wider than 7 mm in diameter.
Stage IB: Clinical lesions confined to the cervix or preclinical lesions greater than stage IA.
Stage IB1: Clinical lesions no greater than 4 cm in size.
Stage IB2: Clinical lesions greater than 4 cm in size.
Stage II
Stage II is carcinoma that extends beyond the cervix but has not extended onto the pelvic wall. The carcinoma involves the vagina, but not as far as the lower third.
Stage IIA: No obvious parametrial involvement. Involvement of up to the upper two thirds of the vagina.
Stage IIB: Obvious parametrial involvement, but not onto the pelvic sidewall.
Stage III
Stage III is carcinoma that has extended onto the pelvic sidewall. On rectal examination, there is no cancer-free space between the tumor and the pelvic sidewall. The tumor involves the lower third of the vagina. All cases with a hydronephrosis or nonfunctioning kidney should be included, unless they are known to be due to other causes.
Stage IIIA: No extension onto the pelvic sidewall but involvement of the lower third of the vagina.
Stage IIIB: Extension onto the pelvic sidewall or hydronephrosis or nonfunctioning kidney.
Stage IV
Stage IV is carcinoma that has extended beyond the true pelvis or has clinically involved the mucosa of the bladder and/or rectum.
Stage IVA: Spread of the tumor onto adjacent pelvic organs.
Stage IVB: Spread to distant organs.
References
1.
Shepherd JH: Cervical and vulva cancer: Changes in FIGO definitions of staging. Br J Obstet Gynaecol 103 (5): 405-6, 1996. [PUBMED Abstract]
2.
Creasman WT: New gynecologic cancer staging. Gynecol Oncol 58(2): 157-158, 1995.
3.
Cervix uteri. In: American Joint Committee on Cancer: AJCC Cancer Staging Manual. 5th ed. Philadelphia, Pa: Lippincott-Raven Publishers, 1997, pp 189-194.
Stage I
Stage I is carcinoma strictly confined to the cervix; extension to the uterine corpus should be disregarded.
Stage IA: Invasive cancer identified only microscopically. All gross lesions even with superficial invasion are stage Ib cancers. Invasion is limited to measured stromal invasion with a maximum depth of 5 mm* and no wider than 7 mm. [Note: *The depth of invasion should not be more than 5 mm taken from the base of the epithelium, either surface or glandular, from which it originates. Vascular space involvement, either venous or lymphatic, should not alter the staging.]
Stage IA1: Measured invasion of the stroma no greater than 3 mm in depth and no wider than 7 mm diameter.
Stage IA2: Measured invasion of stroma greater than 3 mm but no greater than 5 mm in depth and no wider than 7 mm in diameter.
Stage IB: Clinical lesions confined to the cervix or preclinical lesions greater than stage IA.
Stage IB1: Clinical lesions no greater than 4 cm in size.
Stage IB2: Clinical lesions greater than 4 cm in size.
Stage II
Stage II is carcinoma that extends beyond the cervix but has not extended onto the pelvic wall. The carcinoma involves the vagina, but not as far as the lower third.
Stage IIA: No obvious parametrial involvement. Involvement of up to the upper two thirds of the vagina.
Stage IIB: Obvious parametrial involvement, but not onto the pelvic sidewall.
Stage III
Stage III is carcinoma that has extended onto the pelvic sidewall. On rectal examination, there is no cancer-free space between the tumor and the pelvic sidewall. The tumor involves the lower third of the vagina. All cases with a hydronephrosis or nonfunctioning kidney should be included, unless they are known to be due to other causes.
Stage IIIA: No extension onto the pelvic sidewall but involvement of the lower third of the vagina.
Stage IIIB: Extension onto the pelvic sidewall or hydronephrosis or nonfunctioning kidney.
Stage IV
Stage IV is carcinoma that has extended beyond the true pelvis or has clinically involved the mucosa of the bladder and/or rectum.
Stage IVA: Spread of the tumor onto adjacent pelvic organs.
Stage IVB: Spread to distant organs.
References
1.
Shepherd JH: Cervical and vulva cancer: Changes in FIGO definitions of staging. Br J Obstet Gynaecol 103 (5): 405-6, 1996. [PUBMED Abstract]
2.
Creasman WT: New gynecologic cancer staging. Gynecol Oncol 58(2): 157-158, 1995.
3.
Cervix uteri. In: American Joint Committee on Cancer: AJCC Cancer Staging Manual. 5th ed. Philadelphia, Pa: Lippincott-Raven Publishers, 1997, pp 189-194.
