It depends on whether you are talking about marijuana or cigarettes. If you are talking about Marijuana it might but it's not yet proven. Marijuana can cause many effects and defects like stunted growth on new borns and humans enability to produce and if some can produce there are some that loose them and some that carry full term but are born with some type of defect. As far as cigarettes then there are for certain many types of defects but as far as ovarian cyst I'm sort of sure but not really, I have some doubts but you should really check in a book containing information about ovarian cyst.