Well first off, a white, cold toe suggests lack of blood flow to the area. There are many reasons this could have occurred, and I'll listed a few, but please seek medical attention if it persists. First of all, was she exposed to cold for any length of time? If so, it may have been an exaggerated vasoconstriction in that toe; in that case it would resolve upon slow warming of the extremity. You would also expect this not to persist as long as the extremities are kept warm. Raynaud’s is a disease that occurs more commonly in women than men and results in idiopathic (cause unknown) vasoconstriction of the digits and toes (other areas may be affected as well) when exposed to cold or stress. If she has a first degree relative with this, it would make the diagnosis more likely. Another question would be did it occur at rest or while moving around or exercising? If it turned white with activity but resolved upon rest, you might consider things like peripheral artery disease; especially if she has risk factors like smoking, high cholesterol, high blood pressure, etc. To check blood flow you can wait until her toe looks normal then raise her affected leg about 45 degrees in the air (while she is lying down), for 1 minute. If there is paleness to the toe or foot, you would suspect inadequate arterial supply to that area. Pain might also be present. Other things that may cause excessive vasoconstriction are: Smoking, certain OTC cold medicines, some prescription meds, thyroid abnormalities and many others. Bottom line is, if this is recurring or worsening, you definitely want to get it checked out. Also, it might be a good idea to check her pulses when/if this occurs. Check her dorsalis pedis and posterior tibial arteries. Compare to normal foot for symmetry. Hope this helps.
Renaud's Syndrome would cause this.
Arterial occlusion. Get her and her toe to a doctor while there is a chance to save it.
I'm not kidding!
I'm not kidding!
My big toe did this just the other day, for no apparent reason. I was helping my father move a treadmill up three or four steps and into our house, while my boyfriend was picked up by his dad. When I got in the house and took my shoe off, I noticed my left big toe was pale white and tingling, and very cold. It took a minute or two, but it finally regained its color and what little warmth my toes usually have. I don't know what happened, or why it did this, but I hope your wife's toe got better like mine!
I have no clue but my big toe is turning white. And I am freaked out