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Does Lupus Or Fibromyalgia Cause Blisters On Skin?I Woke Up This Morning With A Burning Blister On My Buttock And One Of My Legs. I Rubbed Them And The Skin Came Off And It Feels Like I've Been Burned By Scalding Water.my Skin Is Fire Red .

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Dyshidrotic (or pompholyx) eczema causes blisters similar to the ones you describe, There is an auto-immune disease called pemphigoid which also produces  large blisters.
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I have blisters on my lower leg and it been three months now it does not clear up I waxed my leg and may be it came from that it is very red with blisters

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