Certain medications can make your eyes yellow. It's called jaundice.Jaundice is when the skin and/or the whites of the eyes have a yellow appearance. This happens when the blood has an excess of the pigment called bilirubin. If you aren't taking a medication that may be causing that, you should probably go see the doctor to find out. A simple test should be able to tell the doctor what is wrong. It may be nothing more than a sluggish liver, in which case Milk Thistle may resolve the problem.