How Does The Clinistix Test For Glucose In Urine Work?


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Kath Senior answered
Cliinistix sticks are used commonly in doctors surgeries and hospitals to test for the presence of glucose in urine. This can indicate that someone is developing, or already has, diabetes.

The sticks contain two enzymes, glucose oxidase and peroxidase. The glucose oxidase catalyses the reaction between glucose and oxygen that produces gluconic acid and hydrogen peroxide. The peroxidase catalyses the reaction between the hydrogen peroxide and a pigment in the stick, causing it to change colour.

The intensity of the colour produced is proportional to the amount of glucose present, making this a quantitative test as well as a qualitative test.

The enzymes and pigments are fixed on a celluose fibre pad, which can be easily dipped into a urine sample. The reaction is very quick and within a minute, the colour of the end of the stick can be compared with a chart printed on the stick container, making Clinistix very easy to use.

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